Skip Navigation Links
Discontinuity, Nonlinearity, and Complexity

Dimitry Volchenkov (editor), Dumitru Baleanu (editor)

Dimitry Volchenkov(editor)

Mathematics & Statistics, Texas Tech University, 1108 Memorial Circle, Lubbock, TX 79409, USA

Email: dr.volchenkov@gmail.com

Dumitru Baleanu (editor)

Cankaya University, Ankara, Turkey; Institute of Space Sciences, Magurele-Bucharest, Romania

Email: dumitru.baleanu@gmail.com


Studying the Dynamcis of Neuronal Membrane Using a Numerical Model

Discontinuity, Nonlinearity, and Complexity 6(2) (2017) 185--189 | DOI:10.5890/DNC.2017.06.006

Marina González; Marco Aurélio Santos Granero; Mariana Pelissari Monteiro Aguiar Baroni

Federal Institute of Education, Science and Technology — Campus São Paulo, São Paulo, Brazil

Download Full Text PDF

 

Abstract

The Hodgkin and Huxley model describes the electrophysiology of the membrane of the giant squid’s axon. This model was developed from measurements of passive and active electrical behavior of the nerve cell. The four-coupled nonlinear ordinary differential equations, which describe the model, are based on the behavior of sodium and potassium channels. The aim of this work is to study the dynamic behavior of a neuronal physiological system described by the Hodgkin-Huxley (H-H) model through the analysis and interpretation of numerical simulations.

References

  1. [1]  Roque, Antonio. Introduction to ComputationalNeuroscience - Lesson 5 [internet]. [Accessed on November 17, 2015]. Available in: http://sisne.org/Disciplinas/PosGrad/IntrodNeuroComput/aula5.pdf.
  2. [2]  Hodgkin, A.L. and Huxley, A.F. (1952), A Quantitative Description of Membrane Current and Its Application to Conduction and Excitation in Nerve. Journal of Physiology, 117, 500-544.
  3. [3]  Toxic Proteins Llaboratory of UFRGS (Brazil)- LAPROTOX. [internet]. 2014[Accessed on March 19, 2016]. Available in: http://www.ufrgs.br/laprotox/o-que-fazemos/linhas-de-pesquisa/neurotoxicidade-de-ureases-epeptideos- derivados.
  4. [4]  Aidley, J. D. (1989), The Physiology of Excitable Cells. Cambridge University Press, 3rd ed., Cambridge.
  5. [5]  Kolb, B andWhishaw, I.Q. (2009), An Introduction To Brain and Behavior. 3rd Edition.