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ISSN:2164-6457 (print)
ISSN:2164-6473 (online)
Journal of Applied Nonlinear Dynamics
Miguel A. F. Sanjuan (editor), Albert C.J. Luo (editor)
Miguel A. F. Sanjuan (editor)

Department of Physics, Universidad Rey Juan Carlos, 28933 Mostoles, Madrid, Spain

Email: miguel.sanjuan@urjc.es

Albert C.J. Luo (editor)

Department of Mechanical and Industrial Engineering, Southern Illinois University Ed-wardsville, IL 62026-1805, USA

Fax: +1 618 650 2555 Email: aluo@siue.edu

Optimal Control and Stability Analysis of Malaria Disease: A Model Based Approach

Journal of Applied Nonlinear Dynamics 10(4) (2021) 775--790 | DOI:10.5890/JAND.2021.12.014

Manotosh Mandal$^{1,2}$, Soovoojeet Jana$^{3}$ , U. K. Pahari$^{4}$, T. K. Kar$^{2}$

$^{1}$ Dept. of Mathematics, Tamralipta Mahavidyalaya, Tamluk, Purba Medinipur, West Bengal, India

$^{2}$ Dept. of Mathematics, IIEST, Shibpur, Howrah, West Bengal, India

$^{3}$ Dept. of Mathematics, Ramsaday College, Amt-7111401, Howrah, West Bengal, India

$^{4}$ Department of Mathematics, Netaji Nagar Day College, Kolkata -- 700092

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Abstract

In this paper we have proposed a three dimensional mathematical model on malaria disease by considering two distinct classes namely susceptible and infected human population and infected mosquito population. Basic reproductive number of the system has been obtained and its relation regarding the behavior of the system has been established. Two control parameters, namely treatment control on infected human population and insecticide control on mosquito populations are applied in the present system. We formulate and solve the optimal control problem considering treatment and insecticide as the control variables. All the theoretical results are verified by some computer simulation works.

Acknowledgments

The research work of Dr. Soovoojeet Jana is financially supported by Department of Science \& Technology and Biotechnology, Government of West Bengal (Memo no. 201 (Sanc)/S&T/P/S T/16G-12/2018 dated 19/02/2019). Further, the authors are very much grateful to the anonymous reviewers and Dr. Shanmuganathan Rajasekar, Associate Editor of Journal of Applied Nonlinear Dynamics, for their constructive comments and helpful suggestions, which have helped us significant improvement of the article.

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