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Image of Journal of Applied Nonlinear Dynamics
ISSN:2164-6457 (print)
ISSN:2164-6473 (online)
Journal of Applied Nonlinear Dynamics
Miguel A. F. Sanjuan (editor), Albert C.J. Luo (editor)
Miguel A. F. Sanjuan (editor)

Department of Physics, Universidad Rey Juan Carlos, 28933 Mostoles, Madrid, Spain

Email: miguel.sanjuan@urjc.es

Albert C.J. Luo (editor)

Department of Mechanical and Industrial Engineering, Southern Illinois University Ed-wardsville, IL 62026-1805, USA

Fax: +1 618 650 2555 Email: aluo@siue.edu

Numerical Modeling of Photon Migration in Human Neck Based on the Radiative Transport Equation

Journal of Applied Nonlinear Dynamics 5(1) (2016) 117--125 | DOI:10.5890/JAND.2016.03.009

Hiroyuki Fujii $^{1}$, Shinpei Okawa $^{2}$, Ken Nadamoto$^{3}$, Eiji Okada$^{3}$, Yukio Yamada$^{4}$, Yoko Hoshi$^{5}$, Masao Watanabe$^{1}$

$^{1}$ Division of Space and Mechanical Engineering, Faculty of Engineering, Hokkaido University, Kita 13 Nishi 8, Kita-ku, Sapporo, Japan

$^{2}$ National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama, Japan

$^{3}$ Department of Electronics and Electrical Engineering, Faculty of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama, Kanagawa, Japan

$^{4}$ Brain Science Inspired Life Support Research Center, University of Electro-Communications, 1-5-1 Chofugaoka, Chofu, Japan

5Tokyo Metropolitan Institute of Medical Science, 2-1-6 Kamikitazawa, Setagaya, Tokyo, Japan

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Abstract

Biomedical optical imaging has a possibility of a comprehensive diagnosis of thyroid cancer in conjunction with ultrasound imaging. For improvement of the optical imaging, this study develops a higher order scheme for solving the time-dependent radiative transport equation (RTE) by use of the finite-difference and discrete-ordinate methods. The accuracy and efficiency of the developed scheme are examined by comparison with the analytical solutions of the RTE in homogeneous media. Then, the developed scheme is applied to describing photon migration in the human neck model. The numerical simulations show complex behaviors of photon migration in the human neck model due to multiple diffusive reflection near the trachea.

Acknowledgments

This work is supported in part by Grants-in-Aid for Regional R&D Proposal-Based Program from Northern Advancement Center for Science & Technology of Hokkaido Japan, and the Japan Science and Technology Agency. We would like to express appreciation to Dr. Kazumichi Kobayashi for fruitful discussions.

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